Revised throughout, the 5th Edition presents a complete and up-to-date review and analysis of all aspects of endocrinology, diabetes, and bone metabolism. Readers will also find state-of-the-art information on genetics, proteinomics, and hormone signaling, and coverage of the fields hottest topics in nearly 20 new chapters. Joined by an international team of leading experts (many new to this edition) Drs. Jameson and DeGroot provide guidance that integrates the basic science of endocrinology with clinical medicine and the practical management of endocrine disorders with a clinical focus emphasizes diagnosis and therapy. It organizes information into basic and clinical sections that makes reference quick and easy, and provides tables designed to summarize and organize information, presenting over 1,400 illustrations that clarify complex concepts.