Prions

Prions are infectious, self-propagating proteinaceous agents that cause fatal neurodegenerative diseases, including Creutzfeldt-Jakob Disease (CJD) in humans, scrapie in sheep and goats, and bovine spongiform encephalopathy (BSE) in cattle. In recent years great strides have been made in our understanding of the mechanism of prion propagations and neurotoxicity, however much remains to be discovered. In this book, renowned prion experts review the most recent advances to provide an overview of the field.--