In Screams of Reason, David J. Skal explores our perennial fascination with demented doctors, crazed clinicians, and technology-obsessed fiends. From nineteenth-century Romantic literature to Dr. Strangelove and Hannibal Lecter, the mad scientist proves himself to be a figure of myriad masks and guises - a far more interesting archetype than the nerd-run-amok of B-movies would indicate.

Screams of Reason is an exploration of the prop-laden laboratories of 1930s Hollywood, the mad-science mystique that colors the cult of the computer, the pseudo-science folklore of UFO abductions, and the demonization of doctors and medicine in the brave new world of HMOs and managed care.