Hugh of Singleton, fourth son of a minor knight, has been educated as a clerk, usually a prelude to taking holy orders. However, he feels no real calling—despite his lively faith—and he turns to the profession of surgeon, training in Paris, and then hanging his sign in Oxford.

Soon after, a local lord asks Hugh de Singleton to track the killer of a young woman whose bones have been found in the castle cesspool. Through his medical knowledge, Singleton identifies her as the impetuous missing daughter of a local blacksmith.

The young man she loved—whom she had provoked very publicly—is quickly arrested and sentenced at Oxford. But this is just the beginning of the tale.

The story of Singleton's adventure unfolds with realistic medical procedures, droll medieval wit, romantic distractions, and a consistent underlying sense of Christian compassion.