"Transgenic and knockout mutations provide an important means for understanding gene function, as well as for developing therapies for genetic diseases. This book discusses the many advances in the field of transgenic technology that have enabled researchers to bring about various changes in the mouse genome. Equal emphasis is given to both the principles of transgenic and knockout methods and their applications.

A clear and concise format provides researchers with a comprehensive review of the behavioral paradigms appropriate for analyzing mouse phenotypes." "Researchers in neuroscience, pharmacology, genetics, developmental biology, and cell biology will all find this book essential reading."--BOOK JACKET.