Evan City, a major city in the state of Pennsylvania, is being overrun by a zombie virus. Over the course of 7 days, the entire city is almost completely overrun. The US Military has enforced martial law on the affected areas and has mandated civilians to bunker in their houses with little effect. The city is in chaos and the military is evidently losing. The game focuses on John Creaseman, a local mechanic who realises the government's vain attempts to fight the zombies, attempting to flee the city with his heavily modified and armoured Mustang muscle car, gunning it for the city exit, running over any zombie or soldiers in his way.