Those with the disease develop the telltale sign of a witch: a powerful eye in the center of their forehead. And when that eye opens... the young girl loses herself and becomes a witch that brings destrution and death.

The people of Kevala, struck by a terrible plague of witch disease, live in constant fear of witches. A young country girl named Amalie, who lost both parents to a witch, lives a modest life with her only surviving family, her younger sister Milm.

One fateful day, Milum suddenly disappears. Amalie looks everywhere for Milum, but she is nowhere to be found. Just when Amalie was about to lose hope, Milum returned to the village covered in dirt.

In her hands she carried a Mana Flower, a gift for her beloved sister. But on her forehead she carried the unmistabable mark of the witch..."